Login / Signup

The unexpected co-occurrence of GRN and MAPT p.A152T in Basque families: Clinical and pathological characteristics.

Fermín Moreno-IzcoBegoña IndakoetxeaMyriam BarandiaranMaría Cristina CaballeroAna GorostidiFrancesc CalafellAlazne GabilondoMikel TaintaMiren ZulaicaJosé F Martí MassóAdolfo López de MunainPascual Sánchez-JuanSuzee E Lee
Published in: PloS one (2017)
In our sample, the p.A152T MAPT variant does not appear to show a discernible influence on the clinical phenotype of GRN carriers. Whether p.A152T confers a greater than expected propensity for tau pathology in these GRN carriers remains an open question.
Keyphrases
  • cerebrospinal fluid