Rituximab therapy in ROHHAD(NET) syndrome.
Katherine A C HawtonRainer DoffingerAthimalaipet V RamananSimon C Langton HewerHazel J EvansDinesh GiriJulian P Hamilton ShieldPublished in: Journal of pediatric endocrinology & metabolism : JPEM (2022)
This response possibly reflects an underlying, immune-inflammatory pathology driving excess adiposity in this condition. Potentially, other aspects of ROHHAD(NET) may be mediated through autoimmune dysregulation in which case rituximab may provide benefits for prognosis and survival.