Intraglandular mesenchymal stem cell treatment induces changes in the salivary proteome of irradiated patients.

Charlotte Duch LynggaardRosa Jersie-ChristensenMorten Juhl Siri Beier JensenChristian GrønhøjJacob MelchiorsSøren JacobsenMichael Møller-HansenMikkel HerlyAnnette EkblondJens KastrupAnne Fischer-NielsenDaniel BelstrømChristian von Buchwald

Published in: Communications medicine (2022)

The results indicate an increase in proteins related to tissue regeneration in AT-MSCs treated patients. Our study demonstrates the impact of AT-MSCs on the salivary proteome, thereby providing insight into the potential mode of action of this novel treatment approach.

Keyphrases

mesenchymal stem cells
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
stem cells
bone marrow
umbilical cord
patient reported outcomes
combination therapy
smoking cessation