Clinical Features of COVID-19 on Patients With Neuromyelitis Optica Spectrum Disorders.
Samira Luisa Apostolos-PereiraLis Campos FerreiraMateus BoaventuraNise Alessandra de Carvalho SousaGabriela Joca MartinsJosé Arthur Costa D AlmeidaMilena Sales PitombeiraLucas Silvestre MendesThiago FukudaHideraldo Luíz Souza CabeçaLuciano Chaves RochaBianca Santos de OliveiraCarla Renata Vieira StellaEnedina Maria Lobato de OliveiraLeizian de Souza AmorimAndréa Ferrari de CastroAntonio Pereira Gomes NetoGuilherme Diogo SilvaLucas BuenoMaria de Morais MachadoRafael Castello Dias-CarneiroRonaldo Maciel DiasAlvaro Porto MoreiraAna PiccoloAnderson Kuntz GrzesiukAndre MunizCaio Cesar Diniz DisserolClaudia Ferreira VasconcelosDamacio Kaimen-MacielDenise Sisterolli DinizElizabeth Comini-FrotaFernando Coronetti RochaGutemberg Augusto Cruz Dos SantosYara Dadalti FragosoGuilherme Sciascia Do OlivalHeloisa Helena RuoccoHeloise Helena SiqueiraHenry Koity SatoJosé Alexandre FigueiredoLeandro Cortoni CaliaMario Emilio Teixeira DouradoLetícia ScolariHerval Ribeiro Soares NetoLuiz MelgesMarcus Vinicius Magno GonçalvesMaria Lucia Vellutini PimentelMarlise de Castro RibeiroOmar Gurrola ArambulaPaulo Diniz da GamaRenata Leite MenonRodrigo Barbosa ThomazRogério de Rizo MoralesSilvana SobreiraSuzana Nunes MachadoTaysa Alexandrino Gonsalves Jubé RibeiroValéria Coelho Santa Rita PereiraVanessa Maia CostaAdaucto Wanderley da Nóbrega JuniorSoniza Vieira Alves-LeonMarilia Mamprim de Morais PerinEduardo DonadiTarso AdoniSidney GomesMaria Brito FerreiraDagoberto CallegaroMaria Fernanda MendesDoralina BrumFelipe von Glehn Silvanull nullPublished in: Neurology(R) neuroimmunology & neuroinflammation (2021)
Most NMOSD patients with COVID-19 presented mild disease forms. However, pwNMOSD had much higher odds of hospitalization and intensive care unit admission comparing with the general Brazilian population. The frequency of death was not clearly different. NMOSD disability, DMT type, and comorbidities were not associated with COVID-19 outcome. SARS-CoV2 infection was demonstrated as a risk factor for NMOSD relapses. Collaborative studies using shared NMOSD data are needed to suitably define factors related to COVID-19 severity and neurologic manifestations.