Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells.
Yu Mei QueXiao Qing FanXiao Juan LinXiao Li JiangPing Ping HuXiao Yong TongQun You TanPublished in: RSC advances (2019)
The molecular mechanism of cancer cell death caused by silver nanoparticles (AgNPs) of different sizes is investigated. Compared with the larger nanoparticles, 13 nm AgNPs significantly inhibit the migration and invasiveness of lung adenocarcinoma A549 cells, induce elevated reactive oxygen species and lead to NF-κB directed cellular apoptosis.
Keyphrases
- silver nanoparticles
- cell cycle arrest
- cell death
- pi k akt
- reactive oxygen species
- signaling pathway
- induced apoptosis
- papillary thyroid
- oxidative stress
- endoplasmic reticulum stress
- photodynamic therapy
- cell proliferation
- squamous cell
- lps induced
- squamous cell carcinoma
- lymph node metastasis
- atomic force microscopy
- inflammatory response
- childhood cancer
- single molecule