Amyloid detection and typing yield of skin biopsy in systemic amyloidosis and polyneuropathy.

Sandra PintonElena VacchiGiacomo ChiaroAndrea RaimondiAlexandar TzankovBernhard GerberClaudio GobbiAlain Kaelin-LangGiorgia Melli

Published in: Annals of clinical and translational neurology (2023)

Skin biopsy is a minimally invasive test with optimal sensitivity for amyloid. It allows amyloid typing by electron microscope to identify the precursor protein. The diagnostic work up of systemic amyloidosis should include a skin biopsy.

Keyphrases

ultrasound guided
soft tissue
minimally invasive
fine needle aspiration
wound healing
genetic diversity
binding protein
amino acid
small molecule
label free
drug induced
real time pcr
solar cells