Monitoring and external control of pH in microfluidic droplets during microbial culturing.

Miguel TovarLisa MahlerStefanie BuchheimMartin RothMiriam A Rosenbaum

Published in: Microbial cell factories (2020)

We demonstrated a comparable success of pH monitoring and regulation for fermentations in 1 L scale and 180 pL scale for two E. coli strains. This strategy has the potential to improve cell-based experiments for various microbial systems in microfluidic droplets and opens the possibility for new functional assay designs.

Keyphrases

single cell
high throughput
escherichia coli
microbial community
circulating tumor cells
cell therapy