Endothelial Tyrosine Kinase Tie1 Is Required for Normal Schlemm's Canal Development-Brief Report.

Jing Du Benjamin R Thomson Tuncer OnaySusan E Quaggin

Published in: Arteriosclerosis, thrombosis, and vascular biology (2022)

Tie1 is indispensable for SC development and function, supporting it as a novel target for future SC-targeted glaucoma therapies and a candidate gene for glaucoma in humans.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
optic nerve
endothelial cells
cancer therapy
current status
copy number
gene expression
dna methylation
drug delivery
genome wide identification
genome wide analysis