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Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines.

Olagoke Zacchaeus OlatundeJianping YongCan-Zhong Lu
Published in: ACS omega (2023)
A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC 50 's of 193.5 μM for 24 h and 154.6 μM for 48 h.
Keyphrases
  • breast cancer cells
  • high resolution
  • magnetic resonance
  • anti inflammatory
  • solid state
  • mass spectrometry
  • computed tomography