Magnetic resonance tissue phase mapping demonstrates altered left ventricular diastolic function in children with chronic kidney disease.
Charlotte GimpelBernd A JungSabine JungJohannes BradoDaniel SchwendingerBarbara BurkhardtMartin PohlKatja E OdeningJulia GeigerRaoul ArnoldPublished in: Pediatric radiology (2016)
Tissue phase mapping is feasible in children and adolescents. Children with chronic kidney disease show significantly reduced peak diastolic long- and short-axis left ventricular wall velocities, reflecting impaired early diastolic filling. Thus, tissue phase mapping detects chronic kidney disease-related functional myocardial changes before overt left ventricular hypertrophy or echocardiographic diastolic dysfunction occurs.
Keyphrases
- left ventricular
- chronic kidney disease
- end stage renal disease
- hypertrophic cardiomyopathy
- magnetic resonance
- cardiac resynchronization therapy
- high resolution
- acute myocardial infarction
- heart failure
- aortic stenosis
- left atrial
- mitral valve
- young adults
- high density
- oxidative stress
- ejection fraction
- computed tomography
- coronary artery disease
- atrial fibrillation
- pulmonary hypertension
- transcatheter aortic valve replacement