HIV-1 subtype diversity and immuno-virological outcomes among adolescents failing antiretroviral therapy in Cameroon: A cohort study.
Willy Le Roi Togna PaboJoseph FokamDebimeh NjumeDésiré TakouMaria-Mercedes SantoroRaymond Babila NyasaCollins ChenwiMarie Laure MpouelGrace BeloumouEzechiel Semengue Ngoufack JagniAlex Durand NkaAude Christelle Ka'eGeorges TetoBeatrice DambayaSandrine DjupsaDavy Hyacinthe Gouissi AnguechiaMolimbou EvaristeCedric KamtaLionel BalaVirginie LamboEdie Gregory Halle-EkaneVittorio ColizziCarlo Federico PernoAlexis NdjoloRoland Ndip NdipPublished in: PloS one (2023)
Among APHI in settings like Cameroon, there is a wide genetic diversity of HIV-1, driven by CRF02_AG and with potential novel clades due to ongoing recombination events. Duration of treatment significantly reduces the risk of disease progression.