Assessment of the Role of Selected SMAD3 and SMAD4 Genes Polymorphisms in the Development of Colorectal Cancer: Preliminary Research.

Agnieszka Wosiak Damian Wodziński Katarzyna Michalska Pietrzak Jacek Radzisław Kordek Ewa Balcerczak

Published in: Pharmacogenomics and personalized medicine (2021)

More extensive studies to confirm the results obtained in this study are needed. Further studies on a larger study group divided according to the clinical stage and histological differentiation may allow finding or excluding the significance of the studied SNPs as potential markers of colorectal cancer in relation to the clinico-pathological data.

Keyphrases

epithelial mesenchymal transition
genome wide
transforming growth factor
gene expression
machine learning
signaling pathway
transcription factor
case control
big data
human health
genome wide association