Login / Signup

Thiocillin and micrococcin exploit the ferrioxamine receptor of Pseudomonas aeruginosa for uptake.

Derek C K ChanLori L Burrows
Published in: The Journal of antimicrobial chemotherapy (2021)
Multiple thiopeptides have antimicrobial activity against P. aeruginosa, countering the historical assumption that they cannot cross the outer membrane. These results demonstrate the potential for thiopeptides to act as antipseudomonal antibiotics.
Keyphrases
  • pseudomonas aeruginosa
  • cystic fibrosis
  • biofilm formation
  • acinetobacter baumannii
  • human health
  • risk assessment
  • binding protein
  • drug resistant
  • climate change