Perspective: the essential role of NMR in the discovery and characterization of intrinsically disordered proteins.
H Jane DysonPeter E WrightPublished in: Journal of biomolecular NMR (2019)
The 2019 ISMAR Prize recognized NMR studies of disordered proteins. Here we provide a highly personal perspective on the discovery of intrinsically disordered proteins and the development and application of NMR methods to characterize their conformational ensembles, dynamics, and interactions.