Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis.

Wan-Sheng LiuChen LuBhavesh V Mistry

Published in: Cell & bioscience (2021)

Our IEM data suggest that the PRAMEL1 and PRAMEX1 proteins are not only involved in transcriptional regulation in the nucleus, but may also participate in nucleocytoplasmic transport, and in the formation and function of germ cell-specific organelles during spermatogenesis.

Keyphrases

germ cell
induced apoptosis
cell cycle arrest
electronic health record
big data
signaling pathway
endoplasmic reticulum stress
cell death
oxidative stress
machine learning