RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.

Lei SunArabella WanZhuolong ZhouDongshi ChenHeng LiangChuwei LiuShijia YanYi NiuZiyou LinSiyue ZhanShanfeng WangXianzhang BuWeiling HeXiongbin Lu Anlong Xu Guohui Wan

Published in: Gut (2020)

Collectively, our results reveal a critical metabolism-centric role of RALY in tumour progression, which may lead to cancer therapeutics targeting RALY for treating CRC.

Keyphrases

binding protein
papillary thyroid
oxidative stress
squamous cell
small molecule
genome wide
single cell
cancer therapy
squamous cell carcinoma
gene expression
drug delivery
childhood cancer