BDNF and proBDNF Serum Protein Levels in Obstructive Sleep Apnea Patients and Their Involvement in Insomnia and Depression Symptoms.
Agata GabryelskaSzymon TurkiewiczMarta DitmerFilip Franciszek KarugaDominik StrzeleckiPiotr BiałasiewiczMarcin SochalPublished in: Journal of clinical medicine (2022)
BDNF signaling pathway might be involved in the pathophysiology of depression and insomnia in patients with OSA. BDNF and proBDNF protein levels might be useful in defining OSA phenotypes.
Keyphrases
- obstructive sleep apnea
- sleep quality
- positive airway pressure
- signaling pathway
- end stage renal disease
- depressive symptoms
- stress induced
- ejection fraction
- chronic kidney disease
- newly diagnosed
- protein protein
- prognostic factors
- peritoneal dialysis
- binding protein
- pi k akt
- epithelial mesenchymal transition
- sleep apnea
- patient reported outcomes
- physical activity