Aroylchlorination of 1,6-Dienes via a Photoredox Catalytic Atom-Transfer Radical Cyclization Process.

Quan-Sheng ZhaoGuo-Qiang XuHui LiangZhu-Yin WangPeng-Fei Xu

Published in: Organic letters (2019)

A method using aroyl chlorides as atom-transfer radical cyclization agents in a novel visible-light photocatalytic aroylchlorination reaction is developed. The overall transformation involves the formation of two new C-C bonds and one new C-Cl bond in a one-pot process. The advantages of this reaction include high atom/step/redox economy, mild conditions, operational simplicity, and broad substrate scopes.

Keyphrases

electron transfer
visible light
crystal structure
transition metal
structural basis