Exercise Training Decreases Hepatic Injury and Metastases Through Changes in Immune Response to Liver Ischemia/Reperfusion in Mice.

Hamza O YazdaniChristof KaltenmeierKristin MorderJuik MoonMadelyn TraczekPatricia LoughranRuben ZamoraYoram VodovotzFeng LiJames H-C WangDavid A GellerRichard L SimmonsSamer Tohme

Published in: Hepatology (Baltimore, Md.) (2021)

ExT preconditioning mitigates the inflammatory response to liver IRI, protecting the liver from injury and metastases. In light of these findings, potential may exist for the reduction of liver premetastatic niches induced by liver IRI through the use of ExT as a nonpharmacologic therapy before curative surgical approaches.

Keyphrases

immune response
oxidative stress
type diabetes
mesenchymal stem cells
bone marrow
risk assessment
adipose tissue
blood brain barrier
rectal cancer
high fat diet induced
cerebral ischemia