Coagulopathy, Bleeding Events, and Outcome According to Rotational Thromboelastometry in Patients With Acute Liver Injury/Failure.
R Todd StravitzRobert J FontanaCaitlyn MeinzerValerie Durkalski-MauldinA James HanjeJody C OlsonDavid KochBilal HamidMichael L SchilskyBrendan McGuireDaniel GangerIris LiouConstantine J KarvellasJody A RuleJ P LuyendykKristin ClasenAdrian ReubenMichael CrippsWilliam M Leenull nullPublished in: Hepatology (Baltimore, Md.) (2022)
In patients with ALI/ALF, abnormal ROTEM parameters are frequent and proportional to disease severity. Whether the increased bleeding risk associated with abnormal ROTEM indicates hemostatic failure or is a proxy for disease severity requires additional study.