Percutaneous left atrial appendage occlusion and risk of stroke, hospitalized bleeding and death in Medicare beneficiaries.
Wendy WangLin Yee ChenRob F WalkerAlvaro AlonsoFaye L NorbyKamakshi LakshminarayanPamela L LutseyPublished in: Pharmacoepidemiology and drug safety (2024)
In this analysis of real-world AF patients, percutaneous LAAO versus OAC use was associated with similar risk of death, nonsignificantly elevated risk of stroke, and an elevated risk of bleeding in the post-procedural period. Overall, these results support results of randomized trials that percutaneous LAAO may be an alternative to OAC use for patients with contraindications.
Keyphrases
- atrial fibrillation
- left atrial appendage
- minimally invasive
- ultrasound guided
- end stage renal disease
- catheter ablation
- radiofrequency ablation
- ejection fraction
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- healthcare
- patient reported outcomes
- subarachnoid hemorrhage
- patient reported
- health insurance