Retrospective analysis of neurological findings in esophageal atresia: Allostatic load of disease complexity, cumulative sedation, and anesthesia exposure.
Maggie Jean McMahonDevon Michael EvanovichDanielle Bennet PierMackenzie Shea KaganJue Teresa WangBenjamin ZendejasRussell William JenningsDavid ZurakowskiDusica BajicPublished in: Birth defects research (2023)
We propose that all infants with EA undergo brain imaging in addition to routine spinal imaging given the high burden of abnormal brain/cranial findings in our cohort. Quantification of pain/sedation and anesthesia exposure in long-gap EA patients could be used as indirect markers in future studies assessing the risk of neurological sequelae as evidenced by early abnormalities on brain imaging.
Keyphrases
- high resolution
- resting state
- white matter
- cerebral ischemia
- end stage renal disease
- ejection fraction
- functional connectivity
- newly diagnosed
- chronic kidney disease
- spinal cord
- chronic pain
- mechanical ventilation
- prognostic factors
- peritoneal dialysis
- multiple sclerosis
- photodynamic therapy
- blood brain barrier
- patient reported outcomes
- fluorescence imaging
- current status
- patient reported