BMI, insulin sensitivity, and cognition in early type 2 diabetes: The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study.

José A LuchsingerErin J KazemiDanurys L SanchezMary E LarkinWilly Marcos ValenciaCyrus V DesouzaAnders L CarlsonRodica Pop-BusuiElizabeth R SeaquistHermes J FlorezJoshua Barzilaynull null

Published in: Obesity (Silver Spring, Md.) (2023)

In this study, higher BMI and lower insulin sensitivity in type 2 diabetes were cross-sectionally associated with better cognitive performance. However, only higher BMI was related to cognitive performance when both BMI and insulin sensitivity were considered simultaneously. The causality and mechanisms for this association need to be determined in future studies.

Keyphrases

type diabetes
body mass index
glycemic control
cardiovascular disease
adipose tissue
insulin resistance
emergency department
skeletal muscle
metabolic syndrome
mild cognitive impairment