Older Age and High α-Fetoprotein Predict Higher Risk of Hepatocellular Carcinoma in Chronic Hepatitis-B-Related Cirrhotic Patients Receiving Long-Term Nucleos(t)ide Analogue Therapy.
Yuh-Ying LiuChih-Lang LinCheng-Hao WengPei-Hung ChangCheng-Hung ChienKuang-Chen HuangMan-Chin HuaChing-Chih HuPublished in: Diagnostics (Basel, Switzerland) (2022)
Cirrhotic CHB patients with age <50 years and AFP <8 ng/mL had the lowest annual incidence of HCC. However, those with age ≥50 years or/and AFP ≥8 ng/mL had a significantly higher risk for HCC development and warrant a careful surveillance schedule.