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Combined OX40 Agonist and PD-1 Inhibitor Immunotherapy Improves the Efficacy of Vascular Targeted Photodynamic Therapy in a Urothelial Tumor Model.

Ricardo G AlvimPetrina GeorgalaLucas Mendes NogueiraAlexander J SommaKaran NagarJasmine ThomasLaura AlvimAmelia RiegelChristopher HughesJie ChenAugusto B ReisSouhil LebdaiAvigdor ScherzSteven ZanganehRui GardnerKwanghee KimJonathan A Coleman
Published in: Molecules (Basel, Switzerland) (2021)
Our findings suggest that VTP synergizes with PD-1 blockade and OX40 agonist to promote strong antitumor immune responses, yielding therapeutic efficacy in an animal model of urothelial cancer.
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