Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes.

Pei-Chun ChouChih-Min LiuChing-Hui WengKai-Chien YangMei-Ling ChengYuh-Charn LinRuey-Bing Yang Bai Chuang ShyuSong-Kun ShyueJin-Dian LiuShih-Pin ChenMichael HsiaoYu Feng Hu

Published in: Circulation research (2022)

Fibroblasts drive Aldoc-mediated metabolic reprogramming and rhythmic regulation in SANs. This work details the cellular machinery behind the complex milieu of vertebrate SANs and opens a new direction for future therapy.

Keyphrases

extracellular matrix
stem cells
vena cava
endothelial cells
cell therapy
smoking cessation