Aspirin overcomes cisplatin resistance in lung cancer by inhibiting cancer cell stemness.

Maoyuan ZhaoTing WangZhouguang Hui

Published in: Thoracic cancer (2020)

This study revealed that stemness is a latent inhibitor of the resistance of lung cancer cisplatin-resistant cells and might be effectively inhibited by aspirin.

Keyphrases

low dose
stem cells
induced apoptosis
epithelial mesenchymal transition
cardiovascular events
antiplatelet therapy
signaling pathway
cell cycle arrest
single cell
endoplasmic reticulum stress
cardiovascular disease
oxidative stress
cell death
cancer stem cells
percutaneous coronary intervention