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Extra-corporeal normothermic machine perfusion of the porcine kidney: working towards future utilization in Australasia.

Ahmer M HameedRay MirazizDavid B LuNeil WarwickAli El-AyoubiHeather BurnsYi Vee ChewRoss MatthewsGreg O'GradyLawrence YuenNatasha RogersHenry C PleassWayne J Hawthorne
Published in: ANZ journal of surgery (2017)
A viable and reproducible NMP system was established and tested in porcine kidneys, which was able to simulate graft function extra-corporeally. Further work is required to identify the most optimal perfusion conditions. Prior to its utilization in clinical transplantation, the system should be tested in non-transplanted human kidneys.
Keyphrases
  • endothelial cells
  • contrast enhanced
  • induced pluripotent stem cells
  • deep learning
  • computed tomography
  • magnetic resonance
  • mesenchymal stem cells
  • bone marrow