Clinical Features and Management of Skull Base Fractures in the Pediatric Population: A Systematic Review.
Geena JungJorden XavierHailey ReisertMatthew GoynatskyMargaret KeymakhEmery Buckner-WolfsonTimothy KimRyan FatemiSeyed Ahmad Naseri AlaviAndres PasuizacaPushti ShahGenesis LirianoAndrew J KobetsPublished in: Children (Basel, Switzerland) (2024)
Pediatric basilar skull fractures (BSFs) are a rare type of traumatic head injury that can cause debilitating complications without prompt treatment. Here, we sought to review the literature and characterize the clinical features, management, and outcomes of pediatric BSFs. We identified 21 relevant studies, excluding reviews, meta-analyses, and non-English articles. The incidence of pediatric BSFs ranged from 0.0001% to 7.3%, with falls from multi-level heights and traffic accidents being the primary causes (9/21). The median presentation age ranged from 3.2 to 12.8 years, and the mean age of patients across all studies was 8.68 years. Up to 55% of pediatric BSFs presented with intracranial hematoma/hemorrhage, along with pneumocephalus and edema. Cranial nerve palsies were a common complication (9/21), with the facial nerve injured most frequently (7/21). While delayed cranial nerve palsy was reported in a few studies (4/21), most resolved within three months post-admission. Other complications included CSF leaks (10/21) and meningitis (4/21). Management included IV fluids, antiemetics, and surgery (8/21) to treat the fracture directly, address a CSF leak, or achieve cranial nerve compression. Despite their rarity, pediatric skull base fractures are associated with clinical complications, including CSF leaks and cranial nerve palsies. Given that some of these complications may be delayed, patient education is critical.
Keyphrases
- risk factors
- systematic review
- meta analyses
- healthcare
- emergency department
- ejection fraction
- case control
- minimally invasive
- cerebrospinal fluid
- air pollution
- chronic kidney disease
- metabolic syndrome
- soft tissue
- prognostic factors
- childhood cancer
- young adults
- insulin resistance
- skeletal muscle
- acute coronary syndrome
- quality improvement
- replacement therapy
- smoking cessation