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Prebiotic supplementation does not affect reading and cognitive performance in children: A randomised placebo-controlled study.

Liliana P CapitãoRita BaiãoHee K BaekNils KappelmannRachel SharmanChristopher-James HarveyPaul MontgomeryPhilip W J Burnet
Published in: Journal of psychopharmacology (Oxford, England) (2019)
Based on the emerging interest in the effects of gut microbiota on cognition, this proof-of-concept study assessed how children aged 7 to 9 with low reading scores responded to the ingestion of a 3-month prebiotic supplement versus a placebo. As a secondary aim, the effects of the prebiotic on cognition, sleep, behaviour, mood, anxiety, and cortisol were assessed. In this sample, the prebiotic did not affect any of the outcome measures.
Keyphrases
  • double blind
  • sleep quality
  • clinical trial
  • working memory
  • mild cognitive impairment
  • young adults
  • white matter
  • placebo controlled
  • bipolar disorder
  • physical activity
  • study protocol
  • phase iii