Adenylyl cyclase mRNA localizes to the posterior of polarized DICTYOSTELIUM cells during chemotaxis.

Satarupa DasJoshua M ParkerCan GuvenWeiye WangPaul W KriebelWolfgang LosertDaniel R LarsonCarole A Parent

Published in: BMC cell biology (2017)

Together, our findings suggest that the asymmetric distribution of ACA mRNA allows the local translation and accumulation of ACA protein at the posterior of cells. These data represent a novel functional role for localized translation in the relay of chemotactic signal during chemotaxis.

Keyphrases

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