High CD3+ Cells in Intracranial Thrombi Represent a Biomarker of Atherothrombotic Stroke.

Cyril DargazanliValérie RigauOmer EkerCarlos Riquelme BareiroPaolo MachiGrégory GascouCaroline ArquizanXavier AyrignacIsabelle MourandAstrid CorlobéKyriakos LobotesisNicolas MolinariValérie CostesAlain BonaféVincent Costalat

Published in: PloS one (2016)

The CD3+ T-cell count in intracranial thrombi was significantly higher in "atherothrombotic" origin strokes compared to all other causes. Thrombi with high content of CD3+ cells are more likely to originate from an atherosclerotic plaque.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
coronary artery disease
atrial fibrillation
cell death
signaling pathway
oxidative stress
blood brain barrier
brain injury
optical coherence tomography