A Genomic-Clinicopathologic Nomogram for the Prediction of Lymph Node Invasion in Prostate Cancer.
Zongtai ZhengShiyu MaoZhuoran GuRuiliang WangYadong GuoWentao ZhangXudong YaoPublished in: Journal of oncology (2021)
The proposed nomogram combining the 37-gene-based SVM model with the Gleason grade had the potential to preoperatively predict LNI in PCa. Some of the hub genes should be prioritized for functional studies and mechanistic analyses.
Keyphrases
- prostate cancer
- lymph node
- radical prostatectomy
- genome wide
- copy number
- genome wide identification
- lymph node metastasis
- bioinformatics analysis
- cell migration
- genome wide analysis
- neoadjuvant chemotherapy
- sentinel lymph node
- case control
- network analysis
- transcription factor
- squamous cell carcinoma
- human health
- rectal cancer