Silicone Granulomas at the Peripheral Intravenous Cannula Puncture Site.
Pedro Gil-PallaresIgor Vázquez-OsorioPatricia Pérez-FealJosé Manuel Suárez-PeñarandaPublished in: The American Journal of dermatopathology (2022)
Different adverse reactions to silicone present in cosmetic fillers, implants, or medical devices have been reported. The granulomatous reaction on the injection site due to catheters' silicone coating is an infrequent complication, which may be clinically difficult to suspect. Although the definitive diagnosis requires identification of the silicone with techniques such as X-ray spectroscopy, the possibility of involvement of silicone, as well as the histopathologic demonstration of granulomas with refractile, nonpolarizable, and nonstainable material strongly suggests this diagnosis. Moreover, the use of a low-diaphragm aperture or phase-contrast microscopy could be useful to demonstrate the presence of this, otherwise almost transparent, foreign body.
Keyphrases
- high resolution
- single molecule
- magnetic resonance
- ultrasound guided
- emergency department
- magnetic resonance imaging
- rheumatoid arthritis
- extracorporeal membrane oxygenation
- interstitial lung disease
- optical coherence tomography
- obstructive sleep apnea
- high throughput
- mechanical ventilation
- intensive care unit
- systemic sclerosis
- mass spectrometry
- locally advanced
- low dose
- high speed
- idiopathic pulmonary fibrosis
- rectal cancer
- single cell