Step forward in early recognition of systemic sclerosis: data from the Leiden CCISS cohort.
Sophie I E LiemJacopo CiaffiNina Marijn van LeeuwenMaaike BoonstraSaad AhmedLiesbeth J J Beaart-van de VoordeAnja CorselTalitha DhondaiMaarten K NinaberJ J Miranda Geelhoed-VeltmanMarlies E HeuversMaarten E TushuizenNina Ajmone MarsanPhilippine KièsAnne A SchouffoerThomas Wj HuizingaCornelia F AllaartJeska De Vries-BouwstraPublished in: RMD open (2023)
We observed a decrease in disease duration in Leiden CCISS cohort at cohort entry, possibly indicating more timely diagnosis of SSc. This could provide opportunities for early interventions. While symptom duration at presentation is longer in females, mortality is consistently higher in males, underlining the urge for sex-specific treatment and follow-up.