Investigating the prostate specific antigen, body mass index and age relationship: is an age-BMI-adjusted PSA model clinically useful?

Sean HarrisonKate TillingEmma L TurnerJ Athene LaneAndrew SimpkinMichael DavisJenny DonovanFreddie C HamdyDavid E NealRichard M Martin

Published in: Cancer causes & control : CCC (2016)

Age and BMI were associated with small changes in PSA. An age-BMI-adjusted PSA model is no more clinically useful for detecting prostate cancer than current NICE guidelines. Future studies looking at the effect of different variables on PSA, independent of their effect on prostate cancer, may improve the discrimination of PSA for prostate cancer.

Keyphrases

prostate cancer
radical prostatectomy
body mass index
weight gain
weight loss
case control