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Nalmefene attenuates neural alcohol cue-reactivity in the ventral striatum and subjective alcohol craving in patients with alcohol use disorder.

Damian KarlJ Malte BumbPatrick BachChristina DinterAnne KoopmannDerik HermannKarl MannFalk KieferSabine Vollstädt-Klein
Published in: Psychopharmacology (2021)
In the present study, reduced craving and cue-reactivity to alcohol stimuli in the ventral striatum by nalmefene indicates a potential anti-craving effect of this drug via attenuation of neural alcohol cue-reactivity.
Keyphrases
  • alcohol consumption
  • prefrontal cortex
  • alcohol use disorder
  • spinal cord
  • deep brain stimulation
  • emergency department
  • spinal cord injury
  • depressive symptoms
  • sleep quality