Nalmefene attenuates neural alcohol cue-reactivity in the ventral striatum and subjective alcohol craving in patients with alcohol use disorder.
Damian KarlJ Malte BumbPatrick BachChristina DinterAnne KoopmannDerik HermannKarl MannFalk KieferSabine Vollstädt-KleinPublished in: Psychopharmacology (2021)
In the present study, reduced craving and cue-reactivity to alcohol stimuli in the ventral striatum by nalmefene indicates a potential anti-craving effect of this drug via attenuation of neural alcohol cue-reactivity.