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LogicNet: probabilistic continuous logics in reconstructing gene regulatory networks.

Seyed Amir MalekpourAmir Reza Alizad-RahvarMehdi Sadeghi
Published in: BMC bioinformatics (2020)
The LogicNet reconstructs GRNs and logic functions without requiring prior knowledge of the network structure. Moreover, in another application, the LogicNet can be applied for logic function detection from the known regulatory genes-target interactions. We also conclude that computational modeling of the logical interactions among the regulatory genes significantly improves the GRN reconstruction accuracy.
Keyphrases
  • genome wide
  • transcription factor
  • genome wide identification
  • bioinformatics analysis
  • healthcare
  • genome wide analysis
  • real time pcr
  • gene expression
  • label free
  • loop mediated isothermal amplification