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Lab-on-a-Chip Platforms for Airborne Particulate Matter Applications: A Review of Current Perspectives.

Sharon EzrreMarco A ReynaCitlalli AnguianoRoberto L AvitiaHeriberto Márquez
Published in: Biosensors (2022)
Lab-on-a-Chip (LoC) devices are described as versatile, fast, accurate, and low-cost platforms for the handling, detection, characterization, and analysis of a wide range of suspended particles in water-based environments. However, for gas-based applications, particularly in atmospheric aerosols science, LoC platforms are rarely developed. This review summarizes emerging LoC devices for the classification, measurement, and identification of airborne particles, especially those known as Particulate Matter (PM), which are linked to increased morbidity and mortality levels from cardiovascular and respiratory diseases. For these devices, their operating principles and performance parameters are introduced and compared while highlighting their advantages and disadvantages. Discussing the current applications will allow us to identify challenges and determine future directions for developing more robust LoC devices to monitor and analyze airborne PM.
Keyphrases
  • particulate matter
  • air pollution
  • low cost
  • public health
  • circulating tumor cells
  • high resolution
  • risk assessment
  • mass spectrometry
  • room temperature
  • loop mediated isothermal amplification