Developing a predictive model for metastatic potential in pancreatic neuroendocrine tumor.
Jacques A GreenbergYajas ShahNikolay A IvanovTeagan MarshallScott KulmJelani WilliamsCatherine TranTheresa ScognamiglioJonas J HeymannYeon Joo Lee-SaxtonCaitlin EganSonali MajumdarIrene M MinRasa ZarnegarJames R HoweXavier M KeutgenThomas J Fahey IiiOlivier ElementoBrendan M FinnertyPublished in: The Journal of clinical endocrinology and metabolism (2024)
We identified and validated an eight-gene panel predictive of the metastatic phenotype in PNETs, which can be detected using the clinically-available NanoString nCounter® system. This panel should be studied prospectively to determine its utility in guiding operative versus non-operative management.