Three cases of uncommon medication-associated osteonecrosis of temporal bone.
Hunter VanDolahJason R CrossleyH Jeffrey KimPublished in: World journal of otorhinolaryngology - head and neck surgery (2023)
Anti-resorptive agents and/or tyrosine kinase inhibitors may lead to dysregulation of bone remodeling and result in rare cases of temporal bone osteonecrosis. When a local debridement and antibiotic therapy fail, definitive surgical excision of necrotic bone with subsequent reconstruction of the EAC may offer patients a possible resolution in symptoms.
Keyphrases
- bone mineral density
- soft tissue
- bone loss
- end stage renal disease
- bone regeneration
- newly diagnosed
- chronic kidney disease
- postmenopausal women
- healthcare
- emergency department
- physical activity
- prognostic factors
- peritoneal dialysis
- body composition
- squamous cell carcinoma
- locally advanced
- sleep quality
- mesenchymal stem cells
- cell therapy