Body Mass Index, Adverse Pregnancy Outcomes, and Cardiovascular Disease Risk.
Sadiya S KhanLucia C PetitoXiaoning HuangKatharine HarringtonRebecca B McNeilNatalie A BelloC Noel Bairey MerzEliza C MillerRupa RaviChristina ScifresJanet M CatovVictoria PembertonJasmina VaragicPhyllis C ZeeLynn M YeeMitali RayJin Kyung KimAbbi D Lane-CordovaJennifer LeweyLauren H TheilenGeorge R SaadePhilip GreenlandWilliam A Grobmannull nullPublished in: Circulation research (2023)
There was heterogeneity across APO subtypes in their association with postpartum CVD risk factors and mediation of the association between early pregnancy obesity and postpartum CVD risk factors. However, only a small or nonsignificant proportion of the association between obesity and CVD risk factors was mediated by any of the APOs, suggesting APOs are a marker of prepregnancy CVD risk and not a predominant cause of postpartum CVD risk.