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Treponema pallidum-induced prostaglandin E2 secretion in skin fibroblasts leads to neuronal hyperpolarization: A cause of painless ulcers.

Y HeD-Y YiL PanW-M YeL XieX-Q ZhengD LiuTian-Ci YangY Lin
Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2024)
Treponema pallidum promotes PGE2 secretion in skin fibroblasts, leading to the excitation of neuronal hyperpolarization and potentially contributing to the pathogenesis of painless ulcers in syphilis.
Keyphrases
  • wound healing
  • soft tissue
  • extracellular matrix
  • cerebral ischemia
  • high glucose
  • human immunodeficiency virus
  • men who have sex with men
  • diabetic rats
  • brain injury
  • hiv infected
  • subarachnoid hemorrhage