Rapid production of clinical-grade SARS-CoV-2 specific T cells.

Wing-Hang LeungTeck Guan SohYeh Ching LinnJenny Guek-Hong LowJiashen LohMarieta ChanWee Joo ChngLiang Piu KohMichelle Li-Mei PoonKing Pan NgChik Hong KuickThuan Tong TanLip Kun TanMichaela Su-Fern Seng

Published in: Advances in cell and gene therapy (2020)

High frequencies of rapid antigen-reactive T cells were found in convalescent donors, regardless of severity of COVID-19. The feasibility of clinical-grade production of SARS-CoV-2-specific T cells overnight for therapeutics and diagnostics is revealed.

Keyphrases

sars cov
respiratory syndrome coronavirus
coronavirus disease
small molecule
loop mediated isothermal amplification
single cell
sensitive detection