Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus pooled eggs.

Javier GandaseguiBerta Grau-PujolMaría Cambra-PellejaValdemiro EscolaMaria Antonietta DemontisAnelsio CossaJosé Carlos JamineRafael Balaña-FouceLisette van LieshoutJosé MuñozMaría Martínez-Valladaresnull null

Published in: Parasites & vectors (2021)

We optimized the sample processing methodology and standardized pyrosequencing in soil-transmitted helminth (STH) pooled eggs. These protocols could be used in STH large-scale screenings or anthelmintic efficacy trials.

Keyphrases

molecular docking
phase iii
open label
molecular dynamics simulations