Mechanism of Action of Acupotomy in Inhibiting Chondrocyte Apoptosis in Rabbits with KOA through the PI3K/Akt Signaling Pathway.

Xiao-Shuang HuangKai GengShi-Yu LuoCun-Bin LiuKai-Ning YangAo ZhaiYong-Hui Yang

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

Inhibiting chondrocyte apoptosis in the knee joint of KOA rabbits by upregulating the PI3K/Akt signaling pathway may be a possible mechanism of acupotomy in treating KOA.

Keyphrases

signaling pathway
pi k akt
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
induced apoptosis
epithelial mesenchymal transition
cell death
cell proliferation