SARS-CoV-2 Exposure Investigations Using Genomic Sequencing Among Healthcare Workers and Patients in A Large Academic Center.
Leigh L SmithC Paul MorrisMorgan H JibowuSusan FallonStuart C RaySara E CosgroveMelanie S CurlessValeria M FabreSara M KarabaLisa L MaragakisAaron M MilstoneAnna C Sick-SamuelsPolly TrexlerHeba H MostafaClare Rocknull nullPublished in: Infection control and hospital epidemiology (2022)
SARS-CoV-2 transmissions among healthcare personnel (HCP) and hospitalized patients are challenging to confirm. Investigation of infected persons often reveals multiple potential risk factors for viral acquisition. We combined exposure investigation with genomic analysis confirming two hospital-based clusters. Prolonged close contact with unmasked, unrecognized infectious, individuals was a common risk.