Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function.
Fabian FrostTim KacprowskiMalte Christoph RühlemannMaik PietznerCorinna BangAndre FrankeMatthias NauckUwe VölkerHenry VölzkeMarcus DörrJan BaumbachMatthias SendlerChristian SchulzJulia MayerleFrank U WeissGeorg HomuthMarkus M LerchPublished in: Gut (2020)
This study identifies distinct components of metabolic liver disease to be associated with instability of the intestinal microbiome, increased abundance of facultative pathogens and thus greater susceptibility toward dysbiosis-associated diseases.