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Association of impaired sensitivity to thyroid hormones with hyperuricemia through obesity in the euthyroid population.

Zhiyuan WuYue JiangPingan LiYutao WangHaiping ZhangZhiwei LiXia LiLixin TaoBo GaoXiu-Hua Guo
Published in: Journal of translational medicine (2023)
Our research revealed that BMI mediated the association between impaired sensitivity to thyroid hormones and hyperuricemia in the euthyroid population. These findings could provide useful evidence for understanding the interaction between impaired sensitivity to thyroid hormone and hyperuricemia in euthyroid individuals and suggest the clinical implications of weight control in terms of impaired thyroid hormones sensitivity.
Keyphrases
  • uric acid
  • weight gain
  • body mass index
  • weight loss
  • metabolic syndrome
  • physical activity
  • single cell
  • body weight