Vitiligo surgery: A journey from tissues via cells to the stems!
Muhammed Razmi TT P AfraDavinder ParsadPublished in: Experimental dermatology (2018)
Depigmented patches in vitiligo, a common dermatosis, cause a great psychological distress to the patients. Hence, apart from halting the disease process, the strategies to impart normal skin colour to these white patches carry an important role in the management of vitiligo. Surgical procedures are often required for stable vitiligo lesions not responding to medical therapies. It involves "shuffling" of melanocytes from the pigmented skin to the depigmented areas. During the last fifty years, the vitiligo surgery has evolved from tissue transplantation via cellular transplantation to reach a stage where the use of stem cells or immunomodulatory cells is contemplating. We would like to depict this wonderful journey of vitiligo surgery through this viewpoint.
Keyphrases
- minimally invasive
- coronary artery bypass
- stem cells
- induced apoptosis
- cell cycle arrest
- end stage renal disease
- surgical site infection
- newly diagnosed
- chronic kidney disease
- cell therapy
- ejection fraction
- gene expression
- endoplasmic reticulum stress
- cell death
- prognostic factors
- peritoneal dialysis
- oxidative stress
- soft tissue
- mesenchymal stem cells
- physical activity
- acute coronary syndrome
- depressive symptoms
- sleep quality